Granulocyte‐Colony Stimulating Factor (G‐CSF) as an adjunct to antibiotics in the treatment of pneumonia in adults
AC Cheng, DP Stephens… - Cochrane Database of …, 2004 - cochranelibrary.com
Background Granulocyte colony stimulating factor (G‐CSF) is a naturally‐occurring cytokine
that has been shown to increase neutrophil function and number. Exogenous administration
of recombinant G‐CSF (filgrastim, pegfilgrastim or lenograstim) has found extensive use in
the treatment of febrile neutropaenia, but its role in the treatment of infection in non‐
neutropaenic hosts is less well defined. Objectives We explored the role of G‐CSF as an
adjunct to antibiotics in the treatment of pneumonia in non‐neutropaenic adults.
that has been shown to increase neutrophil function and number. Exogenous administration
of recombinant G‐CSF (filgrastim, pegfilgrastim or lenograstim) has found extensive use in
the treatment of febrile neutropaenia, but its role in the treatment of infection in non‐
neutropaenic hosts is less well defined. Objectives We explored the role of G‐CSF as an
adjunct to antibiotics in the treatment of pneumonia in non‐neutropaenic adults.
Abstract
Background
Granulocyte colony stimulating factor (G‐CSF) is a naturally‐occurring cytokine that has been shown to increase neutrophil function and number. Exogenous administration of recombinant G‐CSF (filgrastim, pegfilgrastim or lenograstim) has found extensive use in the treatment of febrile neutropaenia, but its role in the treatment of infection in non‐neutropaenic hosts is less well defined.
Objectives
We explored the role of G‐CSF as an adjunct to antibiotics in the treatment of pneumonia in non‐neutropaenic adults.
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