Psoriasis is a common, chronic, inflammatory, multisystem disease with predominantly skin
and joint manifestations affecting approximately 2% of the population. In this second of 5
sections of the guidelines of care for psoriasis, we give an overview of psoriatic arthritis
including its cardinal clinical features, pathogenesis, prognosis, classification, assessment
tools used to evaluate psoriatic arthritis, and the approach to treatment. Although patients
with mild to moderate psoriatic arthritis may be treated with nonsteroidal anti-inflammatory …

… Nevertheless, traditional systemic therapies continue to play an important role in the
treatment of psoriasis with their oral route of administration and low cost (compared with
biologics) making them an important treatment option in the appropriate patient. Methotrexate
is the most commonly prescribed traditional systemic therapy worldwide for … Given the long
list of possible drug interactions, a thorough drug history must be obtained from all patients
before initiating treatment with CSA and patients should be educated regarding the …