Gut microbiome of a porcine model of metabolic syndrome and HF-pEF

AN O'Donovan, FM Herisson, F Fouhy… - American Journal …, 2020 - journals.physiology.org
Metabolic syndrome (MetS) is a composite of cardiometabolic risk factors, including obesity,
dyslipidemia, hypertension, and insulin resistance, with a range of secondary sequelae such
as nonalcoholic fatty liver disease and diastolic heart failure. This syndrome has been
identified as one of the greatest global health challenges of the 21st century. Herein, we
examine whether a porcine model of diet-and mineralocorticoid-induced MetS closely
mimics the cardiovascular, metabolic, gut microbiota, and functional metataxonomic …

Gut Microbiome of a Porcine Model of Metabolic Syndrome and HF-pEF

M Caplice - journals.physiology.org
… In order to characterize the porcine model for MetS, body weight, lipid profile and blood
241 … need to be further explored in this pig model in the future. 490 … Figure 2: Temporal
shift of pig fecal microbiome beta diversity in response to Metabolic Syndrome. …
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