HIV-negative Men Who Have Sex with Men have higher CD8+ T-cell Counts and Lower CD4+/CD8+ T-cell Ratios compared to HIV-negative Heterosexual Men
SO Verboeket, FW Wit, E Verheij, RA van Zoest… - J Infect Dis, 2020 - hero.epa.gov
We reported T-cell senescence to be similar in people living with HIV (PWH) with
suppressed viremia (predominantly men who have sex with men (MSM)) and HIV-negative
otherwise comparable controls, but greater than in healthy blood donors. This lead us to
compare CD4+ and CD8+ T-cell counts and CD4+/CD8+ ratios between HIV-negative MSM
and men who only have sex with women (MSW), and relate observed differences to
behavioral factors and infectious exposures, including cytomegalovirus (CMV) infection.
suppressed viremia (predominantly men who have sex with men (MSM)) and HIV-negative
otherwise comparable controls, but greater than in healthy blood donors. This lead us to
compare CD4+ and CD8+ T-cell counts and CD4+/CD8+ ratios between HIV-negative MSM
and men who only have sex with women (MSW), and relate observed differences to
behavioral factors and infectious exposures, including cytomegalovirus (CMV) infection.