[HTML][HTML] Identification of modules and hub genes associated with platinum-based chemotherapy resistance and treatment response in ovarian cancer by weighted …
L Zhang, X Zhang, S Fan, Z Zhang - Medicine, 2019 - journals.lww.com
High-grade serous ovarian carcinoma (HGSOC) is the most prevalent and malignant
ovarian tumor. To identify co-expression modules and hub genes correlated with platinum-
based chemotherapy resistant and sensitive HGSOC, we performed weighted gene co-
expression network analysis (WGCNA) on microarray data of HGSOC with 12 resistant
samples and 16 sensitive samples of GSE51373 dataset. A total of 5122 genes were
included in WGCNA, and 16 modules were identified. Module-trait analysis identified that …
ovarian tumor. To identify co-expression modules and hub genes correlated with platinum-
based chemotherapy resistant and sensitive HGSOC, we performed weighted gene co-
expression network analysis (WGCNA) on microarray data of HGSOC with 12 resistant
samples and 16 sensitive samples of GSE51373 dataset. A total of 5122 genes were
included in WGCNA, and 16 modules were identified. Module-trait analysis identified that …
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