Identification of strain-specific nucleotide sequences in E1 and NS4 genes of rubella virus vaccine strains in Japan
S Katow, H Minahara, T Ota, M Fukushima - Vaccine, 1997 - Elsevier
Strain-specific nucleotide sequences of E1 and NS4 genes in five strains of a live rubella
virus vaccine manufactured in Japan were identified for comparison, using 2389 nucleotides
(1443 nucleotides of the E1 gene, 41 of the 3′ terminal region following the E1 gene and
905 of the NS4 gene). Sequences of the E1 gene in three strains (Matsuura, TCRB19 and
To-336) were identified. Takahashi and Matsuba strains shared common sequences, but
were discriminated by the sequence of the NS4 gene. These five strains showed a …
virus vaccine manufactured in Japan were identified for comparison, using 2389 nucleotides
(1443 nucleotides of the E1 gene, 41 of the 3′ terminal region following the E1 gene and
905 of the NS4 gene). Sequences of the E1 gene in three strains (Matsuura, TCRB19 and
To-336) were identified. Takahashi and Matsuba strains shared common sequences, but
were discriminated by the sequence of the NS4 gene. These five strains showed a …
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