Immunization with Salmonella Abortusequi phage lysate protects guinea pig against the virulent challenge of SAE-742
Salmonella Abortusequi causes important clinical diseases in horses possibly leading to
abortion. In the present investigation, the protective efficacy of both plain and aluminum
hydroxide gel adjuvanted phage lysate was evaluated in guinea pig model. Broad host
range bacteriophage P IZ-SAE-2, was characterized and used for generation of lysates.
Three different lysate batches, produced through separate cycles and characterized, were
pooled together for immunization study. Plain and adjuvanted phage lysate preparations …
abortion. In the present investigation, the protective efficacy of both plain and aluminum
hydroxide gel adjuvanted phage lysate was evaluated in guinea pig model. Broad host
range bacteriophage P IZ-SAE-2, was characterized and used for generation of lysates.
Three different lysate batches, produced through separate cycles and characterized, were
pooled together for immunization study. Plain and adjuvanted phage lysate preparations …
