Impact of High Salt Diet on Cerebral Vascular Function and Stroke in Tff3−/−/C57BL/6N Knockout and WT (C57BL/6N) Control Mice
N Kozina, Z Mihaljević, M Baus Lončar… - International Journal of …, 2019 - mdpi.com
High salt (HS) dietary intake leads to impaired vascular endothelium-dependent responses
to various physiological stimuli, some of which are mediated by arachidonic acid (AA)
metabolites. Transgenic Tff3−/− gene knockout mice (Tff3−/−/C57BL/6N) have changes in
lipid metabolism which may affect vascular function and outcomes of stroke. We aimed to
study the effects of one week of HS diet (4% NaCl) on vascular function and stroke induced
by transient occlusion of middle cerebral artery in Tff3−/− and wild type (WT/C57BL/6N) …
to various physiological stimuli, some of which are mediated by arachidonic acid (AA)
metabolites. Transgenic Tff3−/− gene knockout mice (Tff3−/−/C57BL/6N) have changes in
lipid metabolism which may affect vascular function and outcomes of stroke. We aimed to
study the effects of one week of HS diet (4% NaCl) on vascular function and stroke induced
by transient occlusion of middle cerebral artery in Tff3−/− and wild type (WT/C57BL/6N) …
