Implications of methodological differences in digital electrocardiogram interval measurement
F Badilini, N Sarapa - Journal of electrocardiology, 2006 - Elsevier
Well-specified recommendations have yet to be established on how electrocardiogram
(ECG) interval measurement should be performed by digital on-screen caliper systems to
assess drug-induced effect on cardiac repolarization in pharmaceutical clinical trials with
adequate precision and reproducibility. Since 1997, the industry has followed the European
Committee for Proprietary Medicinal Products Points to Consider by using fully manual
measurement of 3 consecutive sinus rhythm PQRST complexes in 1 lead only (typically limb …
(ECG) interval measurement should be performed by digital on-screen caliper systems to
assess drug-induced effect on cardiac repolarization in pharmaceutical clinical trials with
adequate precision and reproducibility. Since 1997, the industry has followed the European
Committee for Proprietary Medicinal Products Points to Consider by using fully manual
measurement of 3 consecutive sinus rhythm PQRST complexes in 1 lead only (typically limb …
