In vivo detection of thalamic gliosis: a pathoradiologic demonstration in familial fatal insomnia
S Haïk, D Galanaud, MG Linguraru, K Peoc'h… - Archives of …, 2008 - jamanetwork.com
Background Increasing evidence supports the usefulness of brain magnetic resonance
imaging (MRI) for the diagnosis of human prion diseases. From the neuroradiological point
of view, fatal familial insomnia is probably the most challenging to diagnose because brain
lesions are mostly confined to the thalamus. Objective To determine whether multisequence
MRI of the brain can show thalamic alterations and establish pathoradiologic correlations in
a patient with familial fatal insomnia. Design Radioclinical prospective study. We describe a …
imaging (MRI) for the diagnosis of human prion diseases. From the neuroradiological point
of view, fatal familial insomnia is probably the most challenging to diagnose because brain
lesions are mostly confined to the thalamus. Objective To determine whether multisequence
MRI of the brain can show thalamic alterations and establish pathoradiologic correlations in
a patient with familial fatal insomnia. Design Radioclinical prospective study. We describe a …
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