Increased levels of plasma brain-derived neurotrophic factor (BDNF) in children with attention deficit-hyperactivity disorder (ADHD)

SH Shim, Y Hwangbo, YJ Kwon, HY Jeong… - Progress in Neuro …, 2008 - Elsevier
BACKGROUND: Recent reports have suggested a pathophysiological role of brain-derived
neurotrophic factor (BDNF) in attention deficit-hyperactivity disorder (ADHD). We evaluated
the plasma levels of BDNF in patients with ADHD. METHODS: Plasma BDNF levels were
measured in 41 drug naive ADHD patients and 107 normal controls. The severity of ADHD
symptoms was determined by patient scores on the ADHD rating scale (ARS) and the
computerized ADHD diagnostic system (ADS). RESULTS: ANCOVA with age and gender as …

Plasma brain-derived neurotrophic factor (BDNF) in Egyptian children with attention deficit hyperactivity disorder

R El Ghamry, M El-Sheikh, M Abdel Meguid… - Middle East Current …, 2021 - Springer
Background To date, researchers do not fully understand what the aetiology of attention
deficit hyperactivity disorder (ADHD) is. As a neurotrophin, the brain-derived neurotrophic
factor (BDNF) contributes to the growth of neurons as well as to the efficiency and plasticity
of the neuronal synapse, which suggests that it may be a contributing aetiological factor in
ADHD. Therefore, we sought to investigate the relationship between ADHD and plasma
BDNF, including whether there is an association between BDNF and the degree of severity …
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