Individual differences in trait anxiety are associated with white matter tract integrity in the left temporal lobe in healthy males but not females

C Montag, M Reuter, B Weber, S Markett… - Neuroscience, 2012 - Elsevier
The temporal lobe plays a major role in anxiety and depression disorders and is also of
importance for trait anxiety in the non-pathological range. The present study investigates self-
report data of personality dimensions linked to trait anxiety in the context of white matter tract
integrity in the temporal lobes of the human brain in a large sample of N= 110 healthy
participants. The results show that especially in men values for fractional anisotropy of
several white matter tracts in the temporal lobe of the left hemisphere correlate substantially …

Individual differences in trait anxiety are associated with white matter tract integrity in fornix and uncinate fasciculus: preliminary evidence from a DTI based …

S Modi, R Trivedi, K Singh, P Kumar… - Behavioural brain …, 2013 - Elsevier
Trait anxiety, a personality dimension that measures an individual's higher disposition to
anxiety, has been found to be associated with many functional consequences viz. increased
distractibility, attentional bias in favor of threat-related information etc. Similarly, volumetric
studies have reported morphological changes viz. a decrease in the volume of left uncinate
fasciculus (fiber connecting anterior temporal areas including the amygdala with prefrontal-
/orbitofrontal cortices) and an increase in the volume of the left amygdala and right …
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