Infants under 3 months old with cyanosis at the emergency room: could it be gastroesophageal reflux?

M Epifanio, J Eloi, AS Cassiano… - Diseases of the …, 2014 - academic.oup.com
M Epifanio, J Eloi, AS Cassiano, D Pinheiro, JV Spolidoro
Diseases of the Esophagus, 2014academic.oup.com
The aim of this study is to describe the prevalence of gastroesophageal reflux disease (gerd)
in infants under 3 months old with a history of cyanotic episodes, who were examined at the
emergency room of a university hospital. This descriptive study reviews reports of
esophageal pH monitoring from a pediatric gastroenterology service over a period of 5
years. The following data were collected: age, sex, pediatric as well as other specialists'
evaluations, and the esophageal pH monitoring reports. This study included 67 infants with …
Summary
The aim of this study is to describe the prevalence of gastroesophageal reflux disease (GERD) in infants under 3 months old with a history of cyanotic episodes, who were examined at the emergency room of a university hospital. This descriptive study reviews reports of esophageal pH monitoring from a pediatric gastroenterology service over a period of 5 years. The following data were collected: age, sex, pediatric as well as other specialists’ evaluations, and the esophageal pH monitoring reports. This study included 67 infants with a history of cyanotic episodes, with no primary cause determined by pediatrician and pediatric specialists’ evaluations, who underwent esophageal pH monitoring. The infants were 6–90 days old, 41 (61.2%) of them male. Fifty infants (74.6%) had at least one esophageal pH monitoring parameter above the normal limit. ZMD index was abnormal in 32 cases (48%) and reflux index was abnormal in 31 cases (46%). When other common causes of cyanosis have been ruled out, a significant proportion of infants presenting cyanosis have abnormal pH study, suggesting the role of GERD in cyanosis. The authors highlight that reflux index is not enough to conclude whether a pH study is normal or not. The ZMD index and the presence of episodes longer than 20 minutes are also important parameters for GERD diagnosis.
Oxford University Press
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