Infections of cerebrospinal fluid diversion devices in adults: the role of intraventricular antimicrobial therapy
MD Wilkie, MF Hanson, PF Statham, PM Brennan - Journal of Infection, 2013 - Elsevier
OBJECTIVES: The precise role for intraventricular (IVT) antimicrobials in combination with
systemic antibiotics in management of cerebrospinal fluid (CSF) diversion device-associated
infections is uncertain. We evaluated our current practice, comparing dual therapy against
systemic antimicrobials alone. METHODS: All adult patients with at least two consecutive
CSF isolates who were treated for CSF diversion device-related infection over a 5-year
period (2005–2010) were identified retrospectively. Clinical and laboratory parameters …
systemic antibiotics in management of cerebrospinal fluid (CSF) diversion device-associated
infections is uncertain. We evaluated our current practice, comparing dual therapy against
systemic antimicrobials alone. METHODS: All adult patients with at least two consecutive
CSF isolates who were treated for CSF diversion device-related infection over a 5-year
period (2005–2010) were identified retrospectively. Clinical and laboratory parameters …
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