Influence of age, gender, and race on the efficacy of adding ezetimibe to atorvastatin vs. atorvastatin up-titration in patients at moderately high or high risk for coronary …

HE Bays, SE Conard, LA Leiter, SR Bird… - International journal of …, 2011 - Elsevier
BACKGROUND: Age, gender, and race are factors that influence atherosclerotic coronary
heart disease (CHD) risk and may conceivably affect the efficacy of lipid-altering drugs.
METHODS: Post hoc analysis of two multicenter, 6-week, double-blind, randomized, parallel-
group trials assessed age (< 65 and≥ 65years), gender, and race (white, black, and other)
effects on atorvastatin plus ezetimibe versus up-titration of atorvastatin in
hypercholesterolemic patients with CHD risk. High CHD risk subjects with low-density …
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