Influence of pre-exposure to morphine on cannabinoid-induced impairment of spatial memory in male rats

M Farahmandfar, M Kadivar, N Naghdi… - Behavioural brain …, 2013 - Elsevier
In the present study, we investigated the effects of repeated morphine pre-treatment on
impairment of spatial memory acquisition induced by intra dorsal hippocampus (intra-CA1)
administration of the non-selective cannabinoid CB1/CB2 receptor agonist, WIN55, 212-2 in
adult male rats. 2-day version of Morris water maze task has been used for the assessment
of spatial memory. On the training day, rats were trained by a single training session of eight
trials and 24 h later a probe trial test consist of 60 s free swim period without a platform and …
以上显示的是最相近的搜索结果。 查看全部搜索结果