Inhibition of the SOS response of Escherichia coli by the Ada protein
JA Vericat, R Guerrero, J Barbé - Journal of bacteriology, 1988 - Am Soc Microbiol
Induction of the adaptive response by N-methyl-N'-nitro-N-nitrosoguanidine (MNNG) caused
a decrease in the UV-mediated expression of both recA and sfiA genes but not of the
umuDC gene. On the other hand, the adaptive response did not affect the temperature-
promoted induction of SOS response in a RecA441 mutant. The inhibitory effect on the UV-
triggered expression of the recA and sfiA genes was not dependent on either the alkA gene
or the basal level of RecA protein, but rather required the ada gene. Furthermore, an …
a decrease in the UV-mediated expression of both recA and sfiA genes but not of the
umuDC gene. On the other hand, the adaptive response did not affect the temperature-
promoted induction of SOS response in a RecA441 mutant. The inhibitory effect on the UV-
triggered expression of the recA and sfiA genes was not dependent on either the alkA gene
or the basal level of RecA protein, but rather required the ada gene. Furthermore, an …
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