Intranasal oxytocin and a polymorphism in the oxytocin receptor gene are associated with human-directed social behavior in golden retriever dogs

ME Persson, AJ Trottier, J Bélteky, LSV Roth… - Hormones and …, 2017 - Elsevier
The oxytocin system may play an important role in dog domestication from the wolf. Dogs
have evolved unique human analogue social skills enabling them to communicate and
cooperate efficiently with people. Genomic differences in the region surrounding the
oxytocin receptor (OXTR) gene have previously been associated with variation in dogs'
communicative skills. Here we have utilized the unsolvable problem paradigm to investigate
the effects of oxytocin and OXTR polymorphisms on human-directed contact seeking …
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