Lichen planus after HBV vaccination in a child: a case report from Nepal

S Agrawal, VK Garg, A Joshi… - The Journal of …, 2000 - Wiley Online Library
S Agrawal, VK Garg, A Joshi, A Agarwalla, SP Sah
The Journal of dermatology, 2000Wiley Online Library
Vaccination against hepatitis B virus has rarely been associated with lichen planus. We
report a case of this kind in a child from Nepal. A 12‐year‐old boy had developed
generalized itchy violaceous papules and plaques six weeks after the second dose of
hepatitis B virus vaccine. Serum HBsAg and HBeAb were negative, but HBsAb was positive.
New crops of generalized, similar eruptions developed after the booster dose of vaccine. All
the lesions resolved within three months of systemic steroid therapy. There was no …
Abstract
Vaccination against hepatitis B virus has rarely been associated with lichen planus. We report a case of this kind in a child from Nepal. A 12‐year‐old boy had developed generalized itchy violaceous papules and plaques six weeks after the second dose of hepatitis B virus vaccine. Serum HBsAg and HBeAb were negative, but HBsAb was positive. New crops of generalized, similar eruptions developed after the booster dose of vaccine. All the lesions resolved within three months of systemic steroid therapy. There was no recurrence after one year of follow up. Awareness of such an association is necessary, especially in children, because vaccination campaigns are increasing.
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