Luteolin alleviates myocardial ischemia reperfusion injury in rats via Siti1/NLRP3/NF-κB pathway
L Zhao, Z Zhou, C Zhu, Z Fu, D Yu - International Immunopharmacology, 2020 - Elsevier
The purpose of this study was to investigate the effects of luteolin (Lu) on myocardial
ischemia–reperfusion (I/R) injury in rats. I/R model was established by ligating left anterior
descending branch of coronary artery in rats. Cardiac hemodynamic measurement,
myocardial infarction and damage assessment, antioxidant enzymes activities analysis, and
various biochemical indexes of myocardial tissue were measured. Finally, the expression of
proteins levels of Siti1/NLRP3/NF-κB pathway of myocardial tissue in rat were measured by …
ischemia–reperfusion (I/R) injury in rats. I/R model was established by ligating left anterior
descending branch of coronary artery in rats. Cardiac hemodynamic measurement,
myocardial infarction and damage assessment, antioxidant enzymes activities analysis, and
various biochemical indexes of myocardial tissue were measured. Finally, the expression of
proteins levels of Siti1/NLRP3/NF-κB pathway of myocardial tissue in rat were measured by …
