MERIT-HFdescription of the trial

J Wikstrand, MERIT-HF Study Group - Basic Research in Cardiology, 2000 - Springer
… The trial results emphasize the improvement in mortality … In addition, the trial provides
comprehensive information about … to the publication in JAMA, this trial demonstrates that use of …

Metoprolol controlled release/extended release in patients with severe heart failure: analysis of the experience in the MERIT-HF study

S Goldstein, B Fagerberg, Å Hjalmarson… - Journal of the American …, 2001 - jacc.org
… the COPERNICUS trial, in which carvedilol was investigated. The COPERNICUS trial enrolled
… Similar to previous observations in randomized clinical trials with beta-blockers, carvedilol …

… of metoprolol CR/XL and clinical outcomes in patients with heart failure: analysis of the experience in metoprolol CR/XL randomized intervention trial in chronic heart …

J Wikstrand, Å Hjalmarson, F Waagstein… - Journal of the American …, 2002 - jacc.org
Objectives : We performed a post-hoc subgroup analysis in the Metoprolol CR/XL Randomized
Intervention Trial in Chronic Heart Failure (MERIT-HF) with the aim of reporting on the …

Metoprolol CR/XL in female patients with heart failure: analysis of the experience in Metoprolol Extended-Release Randomized Intervention Trial in Heart Failure …

JK Ghali, IL Piña, SS Gottlieb, PC Deedwania… - Circulation, 2002 - Am Heart Assoc
Background— Underrepresentation of women in heart failure clinical trials has limited
conclusions regarding the effect of various management strategies on survival in women with …

… analyses affect clinical practice? Insights from the Metoprolol Succinate Controlled-Release/Extended-Release Randomized Intervention Trial in Heart Failure …

J Wikstrand, H Wedel, J Ghali, P Deedwania… - Cardiac …, 2003 - Springer
… While none of these trials are large enough to provide … performed in the MERIT-HF trial,
and to provide guidance as to … the CIBIS II and COPERNICUS trials in order to obtain more …

Metoprolol CR/XL in postmyocardial infarction patients with chronic heart failure: experiences from MERIT-HF

A Jánosi, JK Ghali, J Herlitz, I Czuriga, M Klibaner… - American heart …, 2003 - Elsevier
… This study is used as a reference because it is a recent prospective randomized trial of β-blocker
usage in post-MI patients with CHF. The combined end point of all-cause mortality/CV …

Economic implications of extended-release metoprolol succinate for heart failure in the MERIT-HF trial: a US perspective of the MERIT-HF trial

JJ Caro, K Migliaccio-Walle, JA O'Brien, W Nova… - Journal of cardiac …, 2005 - Elsevier
… the economic implications of this trial from a US perspective. … This article presents the
economic analyses of this trial. … -up of the trial because the rolling enrolment of the trial leads to …

Consistency of the beneficial effect of metoprolol succinate extended release across a wide range dose of angiotensin-converting enzyme inhibitors and digitalis

JK Ghali, P Dunselman, F Waagstein, S Goldstein… - Journal of cardiac …, 2004 - Elsevier
… The DIG trial, however, predated the widespread use of β-blockers in heart failure, and … trials
that assessed the role of ACEI and β-blockers, the question whether the improvement in trial

[HTML][HTML] Post-myocardial Infarction heart failure: a review on management of drug therapies

G Swaroop - Cureus, 2022 - ncbi.nlm.nih.gov
… In the CAPRICORN trial of carvedilol [13], a multicenter placebo control trial, in which 1959
patients with an acute history of MI and LVEF <40% were randomized. The beneficial effect of …

Clinical study of the month. The MERIT-HF study

H Kulbertus - Revue Medicale de Liege, 1999 - europepmc.org
MERIT-HF study was a multicenter, double-blind randomized placebo-controlled study which
enrolled 3.991 class II-IV heart failure patients with a left ventricular ejection fraction< or= …