MTHFR Gene polymorphisms, B-vitamins and hyperhomocystinemia in young and middle-aged acute myocardial infarction patients

T Angeline, N Jeyaraj, GJ Tsongalis - Experimental and molecular …, 2007 - Elsevier
We have examined the prevalence of the C677T and A1298C single nucleotide
polymorphisms (SNPs) in the methylenetetrahydrofolate reductase (MTHFR) gene in healthy
Tamilians and in patients with acute myocardial infarction and related this polymorphism to
plasma homocysteine concentrations, serum folate, serum cobalamin and riboflavin status.
The SNPs in the MTHFR gene were determined by polymerase chain reaction–restriction
fragment length polymorphism analysis. Plasma homocysteine, serum folate and serum …
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