Metabolic characteristics of soleus muscle in relation to insulin action in the offspring of hypertensive parents
S Kratochvílová, P Vyhnanovská, Z Vlasáková, M Hájek… - Metabolism, 2006 - Elsevier
Insulin resistance affecting skeletal muscle metabolism is present in the prehypertensive
state. The aim of our study was to test the hypothesis that blood pressure value is related to
skeletal muscle composition, measured by 31P magnetic resonance (MR) spectroscopy,
and to insulin sensitivity in the offspring of hypertensive parents (OH) and healthy controls.
Study groups consisted of 10 healthy young lean OH with normal glucose tolerance,
confirmed with oral glucose tolerance test, and 13 controls matched for age, sex, and body …
state. The aim of our study was to test the hypothesis that blood pressure value is related to
skeletal muscle composition, measured by 31P magnetic resonance (MR) spectroscopy,
and to insulin sensitivity in the offspring of hypertensive parents (OH) and healthy controls.
Study groups consisted of 10 healthy young lean OH with normal glucose tolerance,
confirmed with oral glucose tolerance test, and 13 controls matched for age, sex, and body …
METABOLIC CHARACTERISTICS OF SOLEUS MUSCLE IN RELATION TO INSULIN ACTION IN OFFSPRING OF HYPERTENSIVE PARENTS: P 169
S Kratochvilova, Z Vlasakova… - Journal of …, 2004 - journals.lww.com
Objective: To test the hypothesis that insulin action is related to skeletal muscle composition
measured by the 31P and 1H MR Spectroscopy in the offspring of hypertensive parents
(OHP). Design and Methods: Study groups consisted of 10 healthy young lean normotensive
OHP and 13 age-, sex-and body mass index-matched controls (C). Insulin action has been
estimated as glucose disposal (M) and metabolic clearance rate of glucose (MCR) during 6-
hrs hyperinsulinaemic euglycaemic clamp. 1H and 31P MR spectroscopy was performed on …
measured by the 31P and 1H MR Spectroscopy in the offspring of hypertensive parents
(OHP). Design and Methods: Study groups consisted of 10 healthy young lean normotensive
OHP and 13 age-, sex-and body mass index-matched controls (C). Insulin action has been
estimated as glucose disposal (M) and metabolic clearance rate of glucose (MCR) during 6-
hrs hyperinsulinaemic euglycaemic clamp. 1H and 31P MR spectroscopy was performed on …
