Background A high degree of co-morbidity exists between methamphetamine (MA) addiction
and alcohol use disorders and both sequential and simultaneous MA-alcohol mixing
increases risk for co-abuse. As little preclinical work has focused on the biobehavioral
interactions between MA and alcohol within the context of drug-taking behavior, we
employed simple murine models of voluntary oral drug consumption to examine how prior
histories of either MA-or alcohol-taking influence the intake of the other drug. Methods In one …