Modulation of membrane channel currents by gap junction protein mimetic peptides: size matters

J Wang, M Ma, S Locovei… - American Journal of …, 2007 - journals.physiology.org
Connexin mimetic peptides are widely used to assess the contribution of nonjunctional
connexin channels in several processes, including ATP release. These peptides are derived
from various connexin sequences and have been shown to attenuate processes
downstream of the putative channel activity. Yet so far, no documentation of effects of
peptides on connexin channels has been presented. We tested several connexin and
pannexin mimetic peptides and observed attenuation of channel currents that is not …

Modulation of membrane channel currents by gap junction protein mimetic peptides: size

J Wang, M Ma, S Locovei, RW Keane, G Dahl - Biophys J, 2002 - journals.physiology.org
Connexin mimetic peptides are widely used to assess the contribution of nonjunctional
connexin channels in several processes including ATP release. These peptides are derived
from various connexin sequences and have been shown to attenuate processes
downstream of the putative channel activity. Yet so far no documentation of effects of
peptides on connexin channels has been presented. We tested several connexin and
pannexin mimetic peptides and observed attenuation of channel currents that is not …
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