Nano titanium dioxide photocatalytic protein tyrosine nitration: a potential hazard of TiO2 on skin

N Lu, Z Zhu, X Zhao, R Tao, X Yang, Z Gao - Biochemical and biophysical …, 2008 - Elsevier
Protein tyrosine nitration is a prevalent post-translational modification which occurs as a
result of oxidative and nitrative stress, it may be directly involved in the onset and/or
progression of diseases. Considering the existence of nano titanium dioxide (TiO2) in
environment and sunscreen products along with the high content of nitrite in sweat, the UV-
exposed skin may be a significant target for the photosensitized damage. In this paper,
tyrosine nitration of bovine serum albumin (BSA) was initiated in the UV-irradiated reaction …

Nano titanium dioxide photocatalytic protein tyrosine nitration: a potential hazard of TiO2 on skin.

LNH Lu NaiHao, ZZN Zhu ZheNing, ZX Zhao Xuqi… - 2008 - cabidigitallibrary.org
Protein tyrosine nitration is a prevalent post-translational modification which occurs as a
result of oxidative and nitrative stress, it may be directly involved in the onset and/or
progression of diseases. Considering the existence of nano titanium dioxide (TiO2) in
environment and sunscreen products along with the high content of nitrite in sweat, the UV-
exposed skin may be a significant target for the photosensitized damage. In this paper,
tyrosine nitration of bovine serum albumin (BSA) was initiated in the UV-irradiated reaction …
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