Neuropharmacology, pharmacogenetics and pharmacogenomics of aggression: The zebrafish model

MS de Abreu, ACVV Giacomini, R Genario… - Pharmacological …, 2019 - Elsevier
The zebrafish (Danio rerio) is increasingly utilized as a powerful new model organism in
neurobehavioral research. Aggression is a common symptom of many CNS disorders, has
some genetic determinants and can be modulated pharmacologically in humans and animal
model species. Mounting evidence suggests zebrafish as a useful tool to study neurobiology
of aggression, and its pharmacological and genetic regulation. Here, we discuss
mechanisms of zebrafish aggression and their pharmacological, pharmacogenetic and …
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