A bs T r ACT obstructive sleep apnoea (osA) is a complex disease entity strongly influenced
by genetic factors, especially those that affect obesity and fat distribution, upper airway
muscle tone, craniofacial morphology, ventilatory control and sleep, giving rise to the osA
phenotype. osA can also be considered a metabolic syndrome which adversely affects
multiple organ systems, especially the cardiovascular system and the brain. The most widely
used clinical marker for the diagnosis of osA is the apnoea-hypopnoea index, calculated by …