Pharmacokinetics and pharmacodynamics of weekly epoetin beta in lung cancer patients

Y Fujisaka, T Tamura, Y Ohe, H Kunitoh… - … of clinical oncology, 2006 - academic.oup.com
… , we have investigated the pharmacokinetic characteristics of epoetin beta after the initial …
once-weekly repeated dose subcutaneous administration in anemic lung cancer patients. The …

Pharmacokinetics and pharmacodynamics of weekly epoetin beta in lung cancer patients with chemotherapy-induced anemia

Y Fujisaka, T Tamura, Y Ohe, H Kunitoh… - … of Clinical Oncology, 2004 - ascopubs.org
… of reports on pharmacokinetics (PK) with higher dose are available. We carried out the
PK and pharmacodynamic study of epoetin beta (EPOCH) in lung cancer (LC) patients with …

Erythropoietin pharmacology

JM Jurado Garcia, E Torres Sanchez… - … Translational Oncology, 2007 - Springer
… in which epoetin was administered 150 U/kg thrice weekly. … , 17 of them under epoetin alpha
and the rest with epoetin beta. It … 320 patients who were diagnosed with lung cancer under …

New erythropoietic proteins: rationale and clinical data

A Österborg - Seminars in oncology, 2004 - Elsevier
… The pharmacokinetics (PK) of darbepoetin alfa have been … : (A) patients with lung cancer
receiving chemotherapy21 and … 30,000 to 40,000 IU per week of epoetin alfa or epoetin beta. …

[HTML][HTML] Effects of CERA (continuous erythropoietin receptor activator) in patients with advanced non-small-cell lung cancer (NSCLC) receiving chemotherapy: results …

P Gascon, R Pirker, L Del Mastro, L Durrwell - Annals of oncology, 2010 - Elsevier
… μg/kg weekly. Due to observed imbalances in death across … CERA; methoxy polyethylene
glycol-epoetin beta) is a new agent … assessment of safety and pharmacokinetic profile of CERA …

Epoetin beta: a review of its clinical use in the treatment of anaemia in patients with cancer

SM Cheer, AJ Wagstaff - Drugs, 2004 - Springer
… of epoetin beta administered three times weekly in patients … The pharmacokinetics of epoetin
beta have been studied for … were required by patients with non-small cell lung cancer in a …

Epoetin beta in oncology: examining the current evidence

H Ludwig - 2006 - Future Medicine
… of the pharmacokinetics (PK), pharmacodynamics (PD), clinical … Of the patients included,
40% had lung cancer, 13% had … , epoetin beta is approved for use in a 30,000 IU once-weekly

[PDF][PDF] CLINICAL PRACTICE OF RECOMBINANT HUMAN ERYTHROPOETIN IN CANCER RELATED ANEMIA

SV Kumar, GK Thilaka - … Journal of Pharmaceutical Sciences and Research, 2012 - Citeseer
epoetin Beta and darbopoetin Alfa). New concepts for the cure of erythropoietin in cancer
patients include 3 and 4 weekly … in lung cancer patients receiving chemotherapy, J Nat1 cancer

Effects of chemotherapy on endogenous erythropoietin levels and the pharmacokinetics and erythropoietic response of darbepoetin alfa: a randomised clinical trial of …

J Glaspy, D Henry, R Patel, S Tchekmedyian… - … Journal of Cancer, 2005 - Elsevier
pharmacokinetics and pharmacodynamics of endogenous and recombinant human
erythropoietin … observed in our patients, both lasting approximately 1 week. A study in sheep …