Population pharmacokinetics of immunoglobulin intravenous preparation in very low birth weight neonates

MA Tegenge, I Mahmood - International immunopharmacology, 2020 - Elsevier
Background Immunoglobulin products are widely used across multiple therapeutic areas
such as immunodeficiency syndromes, infection and autoimmune diseases. The
pharmacokinetics (PK) of immunoglobulins are well characterized in adults, but very little is
known about the PK of immunoglobulins in neonates and infants (< 2 years of age).
Objective The objectives of the present study were:(1) characterize the PK of
immunoglobulin intravenous preparation using model-independent (non-compartmental …
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