Possibility of chemoprevention by the eradication of Helicobacter pylori: oxidative DNA damage and apoptosis in H. pylori infection.
KB Hahm, KJ Lee, SY Choi, JH Kim… - American Journal of …, 1997 - search.ebscohost.com
Objectives: The purpose of this study was to study the changes of 8-hydroxydeoxyguanosine
(8-OH-dG) contents of DNA from human gastric mucosa with or without Helicobacter pytori
and the changes of two biomarkers, iNOS and apoptosis, in gastric biopsies obtained before
and after the eradication of H. pytori. Methods: DNA isolated from the biopsied human
gastric mucosa was digested to deoxynucleotides by nuclease P1, then with Escherichia coli
alkaline phosphatase, and analyzed by HPLC-ECD system. 8-OH-dG content was …
(8-OH-dG) contents of DNA from human gastric mucosa with or without Helicobacter pytori
and the changes of two biomarkers, iNOS and apoptosis, in gastric biopsies obtained before
and after the eradication of H. pytori. Methods: DNA isolated from the biopsied human
gastric mucosa was digested to deoxynucleotides by nuclease P1, then with Escherichia coli
alkaline phosphatase, and analyzed by HPLC-ECD system. 8-OH-dG content was …
[引用][C] Possibility of chemoprevention by the eradication of Helicobacter pylori: oxidative DNA damage and apoptosis in H. pylori infection.
HKB Hahm KiBaik, LKJ Lee KwangJae… - 1997 - cabidigitallibrary.org
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