[HTML][HTML] Prevalence of pfhrp2 and pfhrp3 gene deletions in Puerto Lempira, Honduras
JF Abdallah, SA Okoth, GA Fontecha, REM Torres… - Malaria journal, 2015 - Springer
Background Recent studies have demonstrated the deletion of the histidine-rich protein 2
(PfHRP2) gene (pfhrp2) in field isolates of Plasmodium falciparum, which could result in
false negative test results when PfHRP2-based rapid diagnostic tests (RDTs) are used for
malaria diagnosis. Although primary diagnosis of malaria in Honduras is determined based
on microscopy, RDTs may be useful in remote areas. In this study, it was investigated
whether there are deletions of the pfhrp2, pfhrp3 and their respective flanking genes in 68 P …
(PfHRP2) gene (pfhrp2) in field isolates of Plasmodium falciparum, which could result in
false negative test results when PfHRP2-based rapid diagnostic tests (RDTs) are used for
malaria diagnosis. Although primary diagnosis of malaria in Honduras is determined based
on microscopy, RDTs may be useful in remote areas. In this study, it was investigated
whether there are deletions of the pfhrp2, pfhrp3 and their respective flanking genes in 68 P …
Prevalence of pfhrp2 and pfhrp3 gene deletions in Puerto Lempira, Honduras
Background Recent studies have demonstrated the deletion of the histidine-rich protein 2
(PfHRP2) gene (pfhrp2) in field isolates of Plasmodium falciparum, which could result in
false negative test results when PfHRP2-based rapid diagnostic tests (RDTs) are used for
malaria diagnosis. Although primary diagnosis of malaria in Honduras is determined based
on microscopy, RDTs may be useful in remote areas. In this study, it was investigated
whether there are deletions of the pfhrp2, pfhrp3 and their respective flanking genes in 68 P …
(PfHRP2) gene (pfhrp2) in field isolates of Plasmodium falciparum, which could result in
false negative test results when PfHRP2-based rapid diagnostic tests (RDTs) are used for
malaria diagnosis. Although primary diagnosis of malaria in Honduras is determined based
on microscopy, RDTs may be useful in remote areas. In this study, it was investigated
whether there are deletions of the pfhrp2, pfhrp3 and their respective flanking genes in 68 P …
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