Procalcitonin as an early diagnostic marker for ventriculoperitoneal shunt infections

R Tomio, T Akiyama, S Shibao, K Yoshida - Surgical infections, 2013 - liebertpub.com
R Tomio, T Akiyama, S Shibao, K Yoshida
Surgical infections, 2013liebertpub.com
Background: Procalcitonin (PCT) has been considered a more reliable marker than others
because of its specificity for bacterial infection. Methods: Case report and review of the
literature. Results: A 50-year-old male was diagnosed with subarachnoid hemorrhage,
intraventricular hemorrhage, and intracerebral hemorrhage. We performed a ruptured
aneurysm clipping and left unilateral external ventricular drainage. We also performed
ventriculoperitoneal (VP) shunt placement in the course; however, VP shunt infection was …
Abstract
Background: Procalcitonin (PCT) has been considered a more reliable marker than others because of its specificity for bacterial infection.
Methods: Case report and review of the literature.
Results: A 50-year-old male was diagnosed with subarachnoid hemorrhage, intraventricular hemorrhage, and intracerebral hemorrhage. We performed a ruptured aneurysm clipping and left unilateral external ventricular drainage. We also performed ventriculoperitoneal (VP) shunt placement in the course; however, VP shunt infection was indicated by fever, increased C-reactive protein concentration and leukocytosis. The cerebrospinal fluid culture showed methicillin-resistant Staphylococcus epidermidis but the serum PCT concentration was quite low.
Conclusions: Although PCT is considered a more reliable serological marker of bacterial meningitis in several reports, the serum PCT concentration did not reflect the bacterial VP shunt infection that was present in our case.
Mary Ann Liebert
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