Putrescine N-acetyltransferase in Onchocerca volvulus and Ascaris suum, an enzyme which is involved in polyamine degradation and release of N-acetylputrescine
RM Wittich, RD Walter - Molecular and biochemical parasitology, 1990 - Elsevier
A novel type of N-acetyltransferase, clearly different from the nuclear and cytosolic
polyamine N-acetyltransferases of mammals, was recently found in the intestinal nematode
Ascaris suum. The occurrence of this putrescine N-acetylating enzyme has also been noted
in the filarial parasite Onchocerca volvulus. The enzyme was partially purified from adults of
O. volvulus and A. suum by chromatography on DEAE-cellulose and cadaverine-Sepharose.
Substrate specificities of the filarial enzyme resemble those of the N-acetyltransferase from …
polyamine N-acetyltransferases of mammals, was recently found in the intestinal nematode
Ascaris suum. The occurrence of this putrescine N-acetylating enzyme has also been noted
in the filarial parasite Onchocerca volvulus. The enzyme was partially purified from adults of
O. volvulus and A. suum by chromatography on DEAE-cellulose and cadaverine-Sepharose.
Substrate specificities of the filarial enzyme resemble those of the N-acetyltransferase from …
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