RNA editing: an overlooked source of fine-scale adaptation in insect vectors?
X Grau-Bové, D Weetman - Current opinion in insect science, 2020 - Elsevier
Highlights•RNA editing introduces transcript-specific mutations that are not detected in
genetic assays.•Regulated RNA editing is conserved and adaptive across various
Drosophila species, suggesting a general principle in insects.•RNA editing fine-tunes the
functions of neural channels that are involved in insecticide resistance.•However, genome-
wide and transcriptome-wide studies of RNA editing in insect vectors are still lacking.RNA
editing is a source of molecular diversity that regulates the functional repertoire of animal …
genetic assays.•Regulated RNA editing is conserved and adaptive across various
Drosophila species, suggesting a general principle in insects.•RNA editing fine-tunes the
functions of neural channels that are involved in insecticide resistance.•However, genome-
wide and transcriptome-wide studies of RNA editing in insect vectors are still lacking.RNA
editing is a source of molecular diversity that regulates the functional repertoire of animal …
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