Current sequence databases now contain numerous whole genome sequences of
pathogenic bacteria. However, many of the predicted genes lack any functional annotation.
We describe an assumption-free approach, Rapid Virulence Annotation (RVA), for the high-
throughput parallel screening of genomic libraries against four different taxa: insects,
nematodes, amoeba, and mammalian macrophages. These hosts represent different
aspects of both the vertebrate and invertebrate immune system. Here, we apply RVA to the …

Rapid Virulence Annotation (RVA): Identification of virulence factors using a bacterial
genome library and multiple invertebrate hosts (vol 105, pg 15967, 2008) :: MPG.PuRe …
Rapid Virulence Annotation (RVA): Identification of virulence factors using a bacterial
genome library and multiple invertebrate hosts (vol 105, pg 15967, 2008) … Rapid
Virulence Annotation (RVA): Identification of virulence factors using a bacterial genome
library and multiple invertebrate hosts (vol 105, pg 15967, 2008). PROCEEDINGS OF THE …