Rearrangement of band 10q22 in leiomyoma and leimyosarcoma of the uterus
M Kiechle-Schwarz, CS Berger, U Surti… - Cancer genetics and …, 1990 - Elsevier
Cytogenetic analysis of a uterine leiomyoma from a 56-year-old woman revealed an
interstitial deletion of chromosome 10, del (10)(q22q24), as the only chromosomal
abnormality. Band 10q22 was also rearranged in a previously reported leiomyosarcoma of
the uterus showing at (10; 17)(q22. 1; p13) as the only change. These findings provide an
additional example in soft tissue tumors for involvement of the same chromosomal regions in
benign and malignant proliferation of cells from the same lineage.
interstitial deletion of chromosome 10, del (10)(q22q24), as the only chromosomal
abnormality. Band 10q22 was also rearranged in a previously reported leiomyosarcoma of
the uterus showing at (10; 17)(q22. 1; p13) as the only change. These findings provide an
additional example in soft tissue tumors for involvement of the same chromosomal regions in
benign and malignant proliferation of cells from the same lineage.
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