Relationship of apolipoprotein E phenotypes to hypocholesterolemia

SM Snyder, JF Terdiman, B Caan, KR Feingold… - The American Journal of …, 1993 - Elsevier
Abstract purpose: Persons with total cholesterol (TC) levels less than 130 mg/dL (less than
3.26 mmol/L) make up less than 1% of a healthy population. Causes of hypocholesterolemia
include a diet very low in cholesterol and saturated fat, disease, genetic factors (including
low apolipoprotein B-100 [apo B-100] and the apo E allele), and drug therapy. The purpose
of this study was to determine the causes of hypocholesterolemia in a healthy Kaiser
Foundation Health Plan (KFHP) population. patients and methods: We conducted a dietary …
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