Chronic alcohol consumption is a well-known risk factor for liver disease. Progression of
alcohol-induced liver disease (ALD) is a multifactorial process that involves a number of
genetic, nutritional and environmental factors. Experimental and clinical studies increasingly
show that oxidative damage induced by ethanol contributes in many ways to the
pathogenesis of alcohol hepatoxicity. Oxidative stress appears to activate AMP-activated
protein kinase (AMPK) signaling system, which has emerged in recent years as a kinase that …