Ropinirole in patients with restless legs syndrome and baseline IRLS total scores≥ 24: efficacy and tolerability in a 26-week, double-blind, parallel-group, placebo …
L Giorgi, A Asgharian, B Hunter - Clinical therapeutics, 2013 - Elsevier
Background As with studies of other dopamine agonists, previously reported studies of
ropinirole in restless legs syndrome (RLS) recruited patients with baseline International
Restless Legs Scale (IRLS) total scores≥ 15. The reported pooled analyses of clinical trials
data suggest benefits of ropinirole in patients with IRLS total scores≥ 24, but the effects of
ropinirole have not been prospectively evaluated in this patient population. Objective The
goal of this study was to evaluate the efficacy and tolerability of ropinirole in patients with …
ropinirole in restless legs syndrome (RLS) recruited patients with baseline International
Restless Legs Scale (IRLS) total scores≥ 15. The reported pooled analyses of clinical trials
data suggest benefits of ropinirole in patients with IRLS total scores≥ 24, but the effects of
ropinirole have not been prospectively evaluated in this patient population. Objective The
goal of this study was to evaluate the efficacy and tolerability of ropinirole in patients with …
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