Sae regulator factor impairs the response to photodynamic inactivation mediated by Toluidine blue in Staphylococcus aureus
Photodynamic inactivation (PDI) involves the combined use of light and a photosensitizer,
which, in the presence of oxygen, originates cytotoxic species capable of inactivating
bacteria. Since the emergence of multi-resistant bacterial strains is becoming an increasing
public health concern, PDI becomes an attractive choice. The aim of this work was to study
the differential susceptibility to Toluidine blue (TB) mediated PDI (TB-PDI) of S. aureus
mutants (RN6390 and Newman backgrounds) for different key regulators of virulence factors …
which, in the presence of oxygen, originates cytotoxic species capable of inactivating
bacteria. Since the emergence of multi-resistant bacterial strains is becoming an increasing
public health concern, PDI becomes an attractive choice. The aim of this work was to study
the differential susceptibility to Toluidine blue (TB) mediated PDI (TB-PDI) of S. aureus
mutants (RN6390 and Newman backgrounds) for different key regulators of virulence factors …
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