Scopolamine impairs memory performance and reduces frontal but not parietal visual P3 amplitude
DD Potter, CD Pickles, RC Roberts, MD Rugg - Biological psychology, 2000 - Elsevier
It has been suggested that the P3 event-related potential (ERP) may mark the operation of
certain working or long-term memory processes. It has also been reported that cholinergic
blockade by scopolamine induces significant memory impairment and is associated with an
increased latency, as well as amplitude reduction or abolition of the auditory P3, thus
supporting hypothesised links between P3 and long-term memory function. An intriguing
anomaly is that, while visual P3 latency is also increased by scopolamine, amplitude is not …
certain working or long-term memory processes. It has also been reported that cholinergic
blockade by scopolamine induces significant memory impairment and is associated with an
increased latency, as well as amplitude reduction or abolition of the auditory P3, thus
supporting hypothesised links between P3 and long-term memory function. An intriguing
anomaly is that, while visual P3 latency is also increased by scopolamine, amplitude is not …
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