Serum insulin-like growth factor-I (IGF-I) and growth in children born after assisted reproduction

C Mau Kai, KM Main, A Nyboe Andersen… - The Journal of …, 2006 - academic.oup.com
Context: Concern has been raised about the safety of assisted reproduction techniques for
the offspring. Objectives: The objective of the study was to investigate postnatal growth and
growth factors in children born after intra-cytoplasmatic sperm injection (ICSI) and in vitro
fertilization (IVF). Design: The study had two cohorts: a population-based longitudinal infant
cohort 0–36 months [236 ICSI, 173 IVF, 1530 naturally conceived (NC)], and a cross-
sectional child cohort at 5 yr (68 ICSI, 67 IVF, 70 NC). Intervention: Anthropometrical …
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