Serum levels of 3-keto-desogestrel after oral administration of desogestrel and 3-keto-desogestrel

HG Hasenack, AMG Bosch, K Käär - Contraception, 1986 - Elsevier
In a cross-over study with orally administered desogestrel (0.150 mg) plus ethinyloestradiol
(0.030 mg) and 3-keto-desogestrel (0.150 mg) plus ethinyloestradiol (0.030 mg) in ten
women under steady-state conditions, the serum levels of 3-keto-desogestrel were
monitored by radioimmunoassay. No statistically significant differences between treatment
groups were found with respect to the areas under the curve of the serum levels versus time
(AUC), peak heights and peak times. The individual AUCs for 3-keto-desogestrel after …
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