Serum osteoprotegerin is increased and independently associated with coronary-artery atherosclerosis in patients with rheumatoid arthritis
Y Asanuma, CP Chung, A Oeser, JF Solus, I Avalos… - Atherosclerosis, 2007 - Elsevier
Osteoprotegerin (OPG), a soluble decoy receptor for receptor activator of nuclear factor κB
ligand, is implicated in the pathogenesis of atherosclerosis. Patients with rheumatoid arthritis
(RA) have inflammation and increased atherosclerosis. We examined the hypothesis that
OPG concentrations are increased in patients with RA and are associated with coronary-
artery atherosclerosis. Serum OPG concentrations were measured by ELISA and coronary-
artery calcification by electron-beam computer tomography in 157 patients with RA and 87 …
ligand, is implicated in the pathogenesis of atherosclerosis. Patients with rheumatoid arthritis
(RA) have inflammation and increased atherosclerosis. We examined the hypothesis that
OPG concentrations are increased in patients with RA and are associated with coronary-
artery atherosclerosis. Serum OPG concentrations were measured by ELISA and coronary-
artery calcification by electron-beam computer tomography in 157 patients with RA and 87 …
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