Sheep gene mapping: assignment of ALDOB, CYP19, WT and SOX2 by somatic cell hybrid analysis

E Payen, N Saidi‐Mehtar, E Pailhoux… - Animal Genetics, 1995 - Wiley Online Library
E Payen, N Saidi‐Mehtar, E Pailhoux, C Cotinot
Animal Genetics, 1995Wiley Online Library
Twenty‐four hamster‐sheep hybrid cell lines representing eleven ovine synteny groups
were used to make syntenic assignments for seven loci ALDOB (aldolase B, fructose
biphosphate); AMH (anti‐Müllerian hormone); CYP19 [cytochrome P450 aromatase,
subfamily XIX (aromatization of androgens)]; WT (Wilms' tumour gene); SOX2 (SRY‐related
HMG‐box gene 2); FSHB (follicle‐stimulating hormone, beta polypeptide); and SRY (sex
region of Y chromosome). These loci were assigned to synteny groups U11 (chr2)(ALDOB); …
Summary
Twenty‐four hamster‐sheep hybrid cell lines representing eleven ovine synteny groups were used to make syntenic assignments for seven loci ALDOB (aldolase B, fructose biphosphate); AMH (anti‐Müllerian hormone); CYP19 [cytochrome P450 aromatase, subfamily XIX (aromatization of androgens)]; WT (Wilms' tumour gene); SOX2 (SRY‐related HMG‐box gene 2); FSHB (follicle‐stimulating hormone, beta polypeptide); and SRY (sex region of Y chromosome). These loci were assigned to synteny groups U11(chr2) (ALDOB); U19 (AMH); U3(chr7) (CYP19); and to chromosomes 15 (WT) and 1 (SOX2). SRY defines the hybrids containing the Y chromosome.
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