Association of methylenetetrahydrofolate reductase gene C677T polymorphism with polycystic ovary syndrome risk: a systematic review and meta-analysis update
L Fu, L Dai, X Li, K Zhang, Y Bai - … Journal of Obstetrics & Gynecology and …, 2014 - Elsevier
Objectives To re-estimate the association between methylenetetrahydrofolate reductase
gene (MTHFR) C677T polymorphism and polycystic ovary syndrome (PCOS) risk by
critically reviewing, analyzing and updating the current evidence. MTHFR C677T
polymorphism has been studied as a possible risk factor for a variety of common conditions
including heart disease, stroke and hypertension. Its association with PCOS was negative in
a previous meta-analysis which had possible shortcomings. More studies have now been …
gene (MTHFR) C677T polymorphism and polycystic ovary syndrome (PCOS) risk by
critically reviewing, analyzing and updating the current evidence. MTHFR C677T
polymorphism has been studied as a possible risk factor for a variety of common conditions
including heart disease, stroke and hypertension. Its association with PCOS was negative in
a previous meta-analysis which had possible shortcomings. More studies have now been …
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