Site-selective orientated immobilization of antibodies and conjugates for immunodiagnostics development

M Shen, JF Rusling, CK Dixit - Methods, 2017 - Elsevier
Immobilized antibody systems are the key to develop efficient diagnostics and separations
tools. In the last decade, developments in the field of biomolecular engineering and
crosslinker chemistry have greatly influenced the development of this field. With all these
new approaches at our disposal, several new immobilization methods have been created to
address the main challenges associated with immobilized antibodies. Few of these
challenges that we have discussed in this review are mainly associated to the site-specific …
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