Solid lipid nanoparticles (SLNs) for intracellular targeting applications

X Calderón-Colón, G Raimondi, JJ Benkoski… - JoVE (Journal of …, 2015 - jove.com
Nanoparticle-based delivery vehicles have shown great promise for intracellular targeting
applications, providing a mechanism to specifically alter cellular signaling and gene
expression. In a previous investigation, the synthesis of ultra-small solid lipid nanoparticles
(SLNs) for topical drug delivery and biomarker detection applications was demonstrated.
SLNs are a well-studied example of a nanoparticle delivery system that has emerged as a
promising drug delivery vehicle. In this study, SLNs were loaded with a fluorescent dye and …
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