Studies on PEG-modified SLNs loading vinorelbine bitartrate (I): preparation and evaluation in vitro
F Wan, J You, Y Sun, XG Zhang, FD Cui, YZ Du… - International journal of …, 2008 - Elsevier
In this study, the conjugate of PEG2000–stearic acid (PEG2000–SA) was used to prepare
PEGylated solid lipid nanoparticles loading vinorelbine bitartrate (VB-pSLNs) by cold
homogenization technique. The particle size and zeta potential of resulted VB-pSLNs
ranged 180–250nm and 0–10mV, which were determined using a Zetasizer, respectively.
Although the drug entrapment efficiency (EE) slightly decreased after the PEG modification
of VB-SLNs, above 60% EE could be reached. The drug release tests in vitro indicated the …
PEGylated solid lipid nanoparticles loading vinorelbine bitartrate (VB-pSLNs) by cold
homogenization technique. The particle size and zeta potential of resulted VB-pSLNs
ranged 180–250nm and 0–10mV, which were determined using a Zetasizer, respectively.
Although the drug entrapment efficiency (EE) slightly decreased after the PEG modification
of VB-SLNs, above 60% EE could be reached. The drug release tests in vitro indicated the …
[PDF][PDF] Studies on PEG modified SLNs loading Vinorelbine Bitartrate (ൕ): Preparation and evaluation in vitro
YZ Du, H Yuan, FQ Hu - 2008 - beyotime.com
In this study, the conjugate of PEG2000-stearic acid (PEG2000-SA) was used to prepare
PEGylated solid lipid nanoparticles loading vinorelbine bitartrate (VB-pSLNs) by cold
homogenization technique. The particle size and Zeta potential of resulted VB-pSLNs
ranged 180-250 nm and 0-10 mV, which were determined using a Zetasizer, respectively.
Although the drug entrapment efficiency (EE) slightly decreased after the PEG modification
of VB-SLNs, above 60% EE could be reached. The drug release tests in vitro indicated the …
PEGylated solid lipid nanoparticles loading vinorelbine bitartrate (VB-pSLNs) by cold
homogenization technique. The particle size and Zeta potential of resulted VB-pSLNs
ranged 180-250 nm and 0-10 mV, which were determined using a Zetasizer, respectively.
Although the drug entrapment efficiency (EE) slightly decreased after the PEG modification
of VB-SLNs, above 60% EE could be reached. The drug release tests in vitro indicated the …
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